Medical Problems During Pregnancy by Carolyn Bernstein & Tamara C. Takoudes
Author:Carolyn Bernstein & Tamara C. Takoudes
Language: eng
Format: epub
Publisher: Springer International Publishing, Cham
Treatment of Lyme Disease
The IDSA guidelines on the treatment of Lyme disease can be seen in Table 5. The management of pregnant woman with Lyme disease differs only in that doxycycline is contraindicated in pregnancy because of the risk of permanent tooth discoloration and possible effect on fetal bone formation. In this patient with early, localized Lyme disease, amoxicillin 500 mg three times per day for 14–21 days would be appropriate. In cases where parental therapy is preferred such as neurologic abnormalities, and some cardiac conditions including high-degree AV block, ceftriaxone is the drug of choice in nonpregnant and pregnant patients alike. It is important to know that Ixodes ticks can be co-infected and transmit Lyme in addition to other pathogens such as Anaplasma phagocytophilum and Babesia spp. If symptoms are not compatible with Lyme disease after a tick bite or symptoms fail to resolve after appropriate antibiotic therapy, these co-infections should be considered [62]. Amoxicillin, which would be used to treat early Lyme disease in pregnant patients, is not effective against either Anaplasma or Babesia, and further investigation and alternative therapies would need to be explored.Table 5Recommended antimicrobial treatment of patients with Lyme disease
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